The OZ Museum is located in Wamego, Kansas. Wamego is located 10 miles east of Manhattan at the intersection of U.S. highway 24 and Kansas highway 99, also known as The Road to OZ.

From Topeka, Kansas City, and points East: Take the Kansas Turnpike west to Topeka. Leave the turnpike at either Topeka exit, following either I-70 or I-470 west. I-470 bypasses Topeka on the south and joins I-70 to the west of the city. Continue west on I-70 to exit 328. You will see the OZ billboards and signs pointing to the exit. Exit 328 is Kansas 99. Follow it 9 miles north to Wamego, where it becomes Lincoln Avenue. The OZ Museum is in the heart of downtown Wamego, on the west side of the street, at 511 Lincoln Avenue.

From Salina, Hays, Denver and points West: Take I-70 east to exit 328. You will see the OZ billboards and signs pointing to the exit. Exit 328 is Kansas 99. Follow it 9 miles north to Wamego, where it becomes Lincoln Avenue. The OZ Museum is in the heart of downtown Wamego, on the west side of the street, at 511 Lincoln Avenue.

From Marysville, Lincoln, Omaha and points North: Drive south on your choice of highways until you reach U.S. 36. Kansas 99 intersects with U.S. 36 twelve miles east of Marysville and 18 miles west of Seneca. Drive 46 miles south on Kansas 99 to Wamego. Kansas 99 intersects with U.S. 24 to the north of Wamego. Continue on into town on the highway, which becomes Lincoln Avenue, Wamego's Main Street. The OZ Museum is in the heart of downtown Wamego, on the west side of the street, at 511 Lincoln Avenue.

From Oklahoma City, Wichita and points South: Drive north on your choice of roads until you can conveniently access the Kansas turnpike, which is I-35 in the southern part of Kansas. If you want to stay on 4 lane highways, take I-135 near the south side of Wichita. It will take you straight north to Salina, where you can take I-70 east, following the directions above. Alternately, you can take the Kansas turnpike (I-35) northeast from Wichita to the Cassoday exit. This puts you on Kansas 177, one of the most beautiful roads in Kansas. This nationally recognized highway goes through the flint hills and directly past the Tallgrass Prairie National Preserve. Continue on Kansas 177 north to I-70, and merge onto I-70 east, exiting 13 miles later at Exit 328. Exit 328 is Kansas 99. Follow it 9 miles north to Wamego, where it becomes Lincoln Avenue. The OZ Museum is in the heart of downtown Wamego, on the west side of the street, at 511 Lincoln Avenue.